Item randomizer basically becomes a must after some playthroughs, because it keeps each run unique. Still irritating you essentially unlock easymode when you find the black knight halberd.
Enemy randomizer runs are also neat, but hard to finish because you might get ganked by late game enemies in small areas like the undead church. Still funny to see Seath or Gwyn appear there.
The boss rush is also worth trying, but doesn't work very well imo. The
poorly translated mod can be funny, but obviously doesn't change much.
Fog gate randomizer is a bit of a hassle and a headache.
There's also daughters of ash but haven't tried it.
Have you played modded ds1 before?